Endocrine Abstracts

Objective: To provide a latent class regression model predictive of surgical outcome in patients with non-functioning macroadenomas (NFMA) of the pituitary gland.Patients and methods: Seventy-five patients with surgically treated NFMA of the pituitary gland were analyzed retrospectively. Thirty-two patients were male. Median age at the time of surgery was 58 years (range: 16–84 years). Median follow-up time was 90 months (range: 14–208 months)....

Objective: 8-Prenylnaringenin (8-PN) is a phytoestrogen discovered in hops. GH3 pituitary adenoma cells of the rat show a variety of responses to phytoestrogens in vitro. This in vitro study aims to analyze changes in hormone expression in GH3 cells treated with 8-PN.Methods: GH3 cells were incubated with 0.5–50 μM 8-PN for 4 h. Medium and ethanol served as controls. Changes in expression of growth hormone (GH) and prolactin (...